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FDA Approves First Gene Therapy for Inherited Deafness: What Otarmeni Means for Patients, Medicine, and Deaf Culture

FDA Approves First Gene Therapy for Inherited Deafness: What Otarmeni Means for Patients, Medicine, and Deaf Culture

Introduction The U.S. Food and Drug Administration has approved the first FDA gene therapy for inherited deafness, a one-time treatment that restored measurable hearing in 80% of evaluable pediatric patients during clinical testing. The therapy, marketed as Otarmeni (lunsotogene parvec-cwha), targets a specific genetic cause of profound hearing loss tied to mutations in the OTOF gene. The decision marks the...

The Deaths of Despair: Part II of The Missing Generation

The Deaths of Despair: Part II of The Missing Generation

Editor’s Note: This is not a position piece on mental health policy, drug enforcement, or the underlying causes of addiction and despair. It is a mathematical observation about the compounding demographic and fiscal impact on nations. The numbers are the numbers — what we do with them is the conversation. If you or someone you know is struggling, the 988...

The Missing Generation How 200 Million Lost Lives Reshaped the West

The Missing Generation: How 200 Million Lost Lives Reshaped the West

Editor’s Note: This is not a position piece on abortion or the right to choose. It is a mathematical observation about the demographic and fiscal impact on nations. The numbers are the numbers — what we do with them is the conversation. The numbers don’t lie, even when polite society wishes they would. Since 1980, the United States has recorded...

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